This newsletter discusses the health and social impacts of synthetic cannabinoids, or ‘Spice’. These substances are linked to severe withdrawal symptoms and negative social effects, particularly among vulnerable groups. Despite their low overall prevalence, usage is higher in certain subpopulations due to their perceived legality and affordability. The risks are amplified by common polydrug use among users, highlighting the need for increased awareness and support.
Cannabimimetic compounds, including cannabinoids, terpenes, and non-cannabinoid constituents, have garnered considerable interest for their interactions with the human endocannabinoid system (ECS). While THC and CBD are widely studied, numerous non-cannabis plants have been found to produce cannabimimetic components that stimulate or modulate the ECS. These compounds can bind to cannabinoid receptors or influence ECS-related enzymes. Such interactions impact physiological processes like neurotransmission, sleep, appetite, mood, and immune response. Alkaloids, terpenes, and other compounds in common herbs and spices exhibit cannabimimetic properties. Understanding and harnessing these compounds hold promise for therapeutic interventions. In this newsletter, we will provide an overview of Cannabis-like compounds beyond the Cannabis genus, highlighting their potential and importance in expanding therapeutic research and drug development.
The relationship between cannabis and anxiety disorders has been getting more and more attention. We’ll discuss the potential benefits of low-dose THC and CBD for anxiety relief, while also addressing the risks associated with frequent cannabis use. Join us to uncover the complexities of using cannabis in treating anxiety disorders and stay informed about the latest research findings in this captivating field.
The cannabis industry has undergone a significant transformation in recent years, and as a result, the number of people using cannabis continues to grow. The total number of U.S. Cannabis Consumers has increased from 28 million in the year 2012 to 52 million in 2022, and is predicted to grow to 69 million by 2030. It seems that this also affects the demographics of cannabis consumers, which in turn shapes the cultural cannabis landscape.